Oxolinic acid

Oxolinic acid Good Supplier In Bulk Supply High Purity 14698-29-4 We provide high quality Oxolinic acid (CAS 14698-29-4), at a very affordable prices to our customers.

1.What is the Oxolinic acid ?

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 μg/ml. Oxolinic acid also blocks neuronal uptake of dopamine in mammals (IC50 = 4.3 μM), leading to an increase in locomotor activity.

Quinolone antibacterial.

2.What is the CAS number for Oxolinic acid ?

The CAS number of Oxolinic acid is 14698-29-4.

More information of Oxolinic acid 14698-29-4 are:

3.What is the molecular formula of Oxolinic acid ?

The chemical formula of?Oxolinic acid is C13H11NO5 which containing 13 Carbon atoms,11 Hydrogen atoms,1 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight, and the molecular weight of Oxolinic acid is 261.234

4.What is Oxolinic acid(14698-29-4)used for?

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Oxolinic acid is a quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 μg/ml. Oxolinic acid also blocks neuronal uptake of dopamine in mammals (IC50 = 4.3 μM), leading to an increase in locomotor activity.

InChI:InChI=1/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

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5.Oxolinic acid Good Supplier In Bulk Supply High Purity 14698-29-4

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