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1.What is the Dideoxyinosine ?
Didanosine is an orally active purine dideoxynucleoside analog indicated for adult and pediatric patients with advanced HIV infection who are either intolerant or significantly deteriorated on zidovudine. It appears to increase CD4 cell counts and decrease p24 antigen levels.Major adverse effects are pancreatitis, peripheral neuropathy and diarrhea.Unlike zidovudine, didanosine exhibits insignificant bone marrow suppression.
Didanosine (ddI, Videx) is an adenosine analogue with activity against HIV-1, HIV-2, and HTLV-I. It is approved as part of a multidrug regimen for the therapy of HIV infection and is also used as postexposure HIV prophylaxis
2?,3?-Dideoxyinosine is a potent anti-retroviral agent. It is most effective in combination therapy for the treatment of HIV and related lymphoma.
2.What is the CAS number for Dideoxyinosine ?
The CAS number of Dideoxyinosine is 69655-05-6.
More information of Dideoxyinosine 69655-05-6 are:
|
CAS?Number |
69655-05-6 |
|
Density |
1.76 g/cm3 |
|
Melting Point |
193-195 °C |
|
Boiling Point |
586.5 °C at 760 mmHg |
|
Flash Point |
308.5 °C |
|
Vapor Pressure |
1.33E-14mmHg at 25°C |
|
Refractive Index |
-28 ° (C=0.34, H2O) |
|
HS CODE |
29335990 |
|
Pka |
9.12(at 25℃) |
3.What is the molecular formula of Dideoxyinosine ?
The chemical formula of?Dideoxyinosine is C10H12N4O3 which containing 10 Carbon atoms,12 Hydrogen atoms,4 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight, and the molecular weight of Dideoxyinosine is 236.23
4.What is Dideoxyinosine(69655-05-6)used for?
Didanosine is an orally active purine dideoxynucleoside analog indicated for adult and pediatric patients with advanced HIV infection who are either intolerant or significantly deteriorated on zidovudine. It appears to increase CD4 cell counts and decrease p24 antigen levels.Major adverse effects are pancreatitis, peripheral neuropathy and diarrhea.Unlike zidovudine, didanosine exhibits insignificant bone marrow suppression.
InChI:InChI=1/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)
Relevant articles related to Dideoxyinosine:
|
Article |
Source |
|
A new synthesis of 2',3'-dideoxyinosine |
Bhat,Stocker,Ugarkar , p. 1481 - 1486 (1992) |
|
Continuous flow photochemistry for the rapid and selective synthesis of 2′-deoxy and 2′,3′-dideoxynucleosides |
Shen, Bo,Jamison, Timothy F. , p. 157 - 164 (2013/04/10) |
5.Dideoxyinosine GMP Manufacturer Global Trade 69655-05-6 with Fast Delivery
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