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D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)

Cas number：866607-35-4
purity：99%

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Quality products?make an important contribution to long-term revenue and profitability. Buy reliable Quality D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) 866607-35-4 raw material with Honest Price

1.What is the D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) ?

The title compound is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.

: 842133-18-0,1589590-87-3
canagliflozin

: 108-24-7
acetic anhydride

: 866607-35-4
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Conditions

Conditions	Yield
With dmap; triethylamine; In ethyl acetate; at 20 - 30 ℃; for 1h;	80%
With 4-methyl-morpholine; dmap; In tetrahydrofuran; at -10 - 20 ℃; for 1.25h;	78%
With 4-methyl-morpholine; dmap; In dichloromethane; at -5 - 5 ℃; for 4h; Reagent/catalyst;	69.5%
With 4-methyl-morpholine; dmap; In tetrahydrofuran; at -10 - 20 ℃; for 1.25h;
With dmap; In acetone; at 0.25 - 0.5 ℃; for 5h;	7.2 g
With dmap; triethylamine; In tetrahydrofuran; at 5 - 25 ℃; for 2h;	86 g

: 898566-17-1
(2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene)

: 572-09-8
2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

: 866607-35-4
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Conditions

Conditions	Yield
(2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene); With isopropylmagnesium chloride; In tetrahydrofuran; at 0 - 10 ℃; for 2h; Inert atmosphere; 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide; In tetrahydrofuran; at -15 - 10 ℃; for 2h; Reagent/catalyst; Inert atmosphere;	86.2%
With bis(acetylacetonate)nickel(II); magnesium chloride; 4,4',4-tri-tert-butyl-2,2':6',2-terpyridine; zinc; In tetrahydrofuran; for 20h; Schlenk technique; Inert atmosphere; Cooling with ice;	75%
With magnesium chloride; In tetrahydrofuran; at 15 ℃; stereoselective reaction;	60%

2.What is the CAS number for D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) ?

The CAS number of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) is 866607-35-4.

More information of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) 866607-35-4 are:

CAS?Number	866607-35-4
Density	1.32±0.1 g/cm3(Predicted)
Melting Point	160-170 °C
Boiling Point	658.3±55.0 °C(Predicted)
Vapor Pressure	0Pa at 20℃
PSA	142.67000
LogP	5.25150

3.What are another words for D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) ?

Synonyms?for?D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) 866607-35-4:D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI);(2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate;(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol tetraacetate;Canagliflozin Impurity 11;Tetra Acetyl Canagliflozin

4.What is the molecular formula of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)?

The chemical formula of ?D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) is?C32H33FO9S which containing 32 Carbon atoms,33 Hydrogen atoms,1 Fluorine atoms,9 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)?is 612.673.

5.What is D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) (866607-35-4) used for?

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)(9CI) is a complex organic compound that serves as an intermediate in the synthesis of Canagliflozin. D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)(9CI) plays a crucial role in the development of pharmaceuticals targeting type 2 diabetes and obesity.

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6.Buy D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) with the best price .

Shijiazhuang Saiya Chemical Co., Ltd is a quality supplier of D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI). Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) 866607-35-4.

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