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What is the PENICILLIC ACID ?
PENICILLIC ACID is slight yellow powder, while it's Molecular Formula is C8H10 O4. Penicillic acid can be isolated from the seed-borne fungus Aspergillus persii EML-HPB1-11 and it exhibits antibacterial activity against various plant pathogenic bacteria. PENICILLIC ACID can be a potential lead molecule for developing synthetic agrochemicals. Penicillic acid is also used as a quorum sensing inhibitor.
What is the CAS number for PENICILLIC ACID ?
The CAS number of PENICILLIC ACID is 90-65-3.
More information of PENICILLIC ACID 90-65-3 are:
|
Synonyms |
Penicillicacid (6CI); 3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid; NSC 402844; g-keto-b-Methoxy-d-methylene-Da-hexenoicacid |
|
CAS?Number |
90-65-3 |
|
Molecular Formula |
C8H10 O4 |
|
Molecular Weight |
170.18 |
|
Density |
1.157 g/cm3 |
|
Melting Point |
83-87 °C |
|
Boiling Point |
285.7 °C at 760 mmHg |
|
Flash Point |
113.5 °C |
|
HS CODE |
29189900 |
|
PSA |
63.60000 |
|
LogP |
0.74650 |
|
Pka |
3.90±0.33(Predicted) |
What is PENICILLIC ACID (90-65-3) used for?
Gram negative bacteria utilize N-acylated homoserine lactones to coordinate expression of virulence in response to the density of the surrounding bacterial population in a process termed quorum sensing. By interfering with this communication and thereby disrupting virulence expression, quorum sensing inhibitors are emerging as an alternative to the conventional ways of fighting bacterial infections. Penicillic acid is a mycotoxin produced from Penicillium species identified in molds on corn and other grains. At 80 μM, penicillic acid inhibits bacterial quorum sensing communication in P. aeruginosa by selectively repressing various virulence factor and other quorum sensing-regulated genes. It has been shown to inhibit Fas-mediated apoptosis at 100-200 μM by targeting caspase-8 activity in Burkitt’s lymphoma Raji cells.
InChI:InChI=1/C8H10O4/c1-5(2)8(11)6(12-3)4-7(9)10/h4H,1H2,2-3H3,(H,9,10)/p-1
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