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Product Details
Chinese Manufacturer Supply DIMETHYL(3-PHENOXY-2-OXOPROPYL)PHOSPHONATE 40665-68-7 On Stock with Competitive Price
- Molecular Formula: C11H15O5P
- Molecular Weight: 258.211
- Vapor Pressure: 1.16E-05mmHg at 25°C
- Refractive Index: 1.491
- Boiling Point: 369.8 °C at 760 mmHg
- Flash Point: 191.1 °C
- PSA: 71.64000
- Density: 1.21 g/cm3
- LogP: 2.12040
DIMETHYL(3-PHENOXY-2-OXOPROPYL)PHOSPHONATE(Cas 40665-68-7) Usage
InChI:InChI=1/C11H15O5P/c1-14-17(13,15-2)9-10(12)8-16-11-6-4-3-5-7-11/h3-7H,8-9H2,1-2H3
40665-68-7 Relevant articles
He fluorine front row element intermediate preparation method (by machine translation)
-
Paragraph 0034; 0035; 0036, (2018/05/16)
The invention discloses he fluorine fron...
Preparation method of beta-carboxyl phosphate
-
Paragraph 0086; 0089; 0090, (2017/09/01)
The invention provides a preparation met...
Synthesis of (±) travoprost and its analogs
Mudduluru, Harikrishna,Hindupur, Rama M.,Dubey, Pramod K.,Madhavaram, Shankar,Tatini, Lakshmikumar,Subbaraju, Gottumukkala V.
experimental part, p. 234 - 241 (2012/04/18)
A new synthetic approach for the antigla...
PROSTANOIDS. XXX. SYNTHESIS OF THE ANALOGS OF 11-DEOXYPROSTA-GLANDINS E AND F
Tolstikov, G. A.,Miftakhov, M. S.,Adler, M. E.,Platonov, V. E.,Sagitdinova, Kh. F.,Khalilov, L. M.
, p. 100 - 107 (2007/10/02)
A practical approach to 11-deoxyprostagl...
40665-68-7 Process route
-
-
2065-23-8
methyl 2-phenoxyacetate
-
-
756-79-6
dimethyl methane phosphonate
-
-
40665-68-7
dimethyl (3-phenoxy-2-oxopropyl)phosphonate
| Conditions | Yield |
|---|---|
|
dimethyl methane phosphonate;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Inert atmosphere;
methyl 2-phenoxyacetate;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 2.5h;
Inert atmosphere;
|
83%
|
|
dimethyl methane phosphonate;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
Inert atmosphere;
methyl 2-phenoxyacetate;
In
tetrahydrofuran;
at 25 ℃;
|
25%
|
|
With
n-butyllithium;
Yield given. Multistep reaction;
1.) THF, hexane, -78 deg C, 5 min, 2.) -78 deg C, 2 h;
|
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane; water;
|
-
-
2555-49-9
phenoxyacetic acid ethyl ester
-
-
756-79-6
dimethyl methane phosphonate
-
-
40665-68-7
dimethyl (3-phenoxy-2-oxopropyl)phosphonate
| Conditions | Yield |
|---|---|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
|
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
|
40665-68-7 Upstream products
-
2065-23-8
methyl 2-phenoxyacetate
-
34939-91-8
dimethyl lithiomethylphosphonate
-
756-79-6
dimethyl methane phosphonate
-
709-84-2
bis-tetrahydropyran-2-yl ether
40665-68-7 Downstream products
-
871669-32-8
7α-hydroxy-6β-(3'-oxo-4'-phenoxy-1'E-butenyl)-2-oxabicyclo <3.3.0> octan-3-one 3.3.0>
-
871669-30-6
7α-trimethylsilyloxy-6β-(3'-oxo-4'-phenoxy-1'E-butenyl)-2-oxabicyclo <3.3.0> octan-3-one 3.3.0>
-
87929-54-2
(Z)-7-[(1S,2R,3S,4R)-3-((E)-3-Oxo-4-phenoxy-but-1-enyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester
-
122437-70-1
methyl 9,15-dioxo-16-phenoxy-13-trans-17,18,19,20-tetranorprostenoate
DIMETHYL(3-PHENOXY-2-OXOPROPYL)PHOSPHONATE
CAS:40665-68-7
Purity:99%
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